Identification of novel genes and pathways affecting Salmonella type III secretion system 1 using a contact-dependent hemolysis assay.
نویسندگان
چکیده
We screened 5,700 Salmonella enterica serovar Typhimurium mutants for defects in type III secretion system 1 (T3SS-1)-mediated contact-dependent hemolysis to identify novel genes and pathways affecting the activity of T3SS-1. Our data suggest that previously unrecognized factors such as type I fimbriae may modulate the expression, activity, or deployment of this key virulence factor.
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ورودعنوان ژورنال:
- Journal of bacteriology
دوره 190 9 شماره
صفحات -
تاریخ انتشار 2008